Endocrine Abstracts

Introduction and Aims: A higher prevalence of hyperglycemia has been reported in patients affected by coronavirus disease 2019 (COVID-19). Our study aims to retrospectively evaluate the course of hyperglycemia in patients recovering from COVID-19.Methods: All patients who were hospitalised in Çanakkale Onsekiz Mart University Hospital between March 2020 and March 2022 due to COVID-19 and whose HbA1c values were checked during hospitalisation were ex...

Introduction: Hyperkalemia due to zona glomerulosa (ZG) insufficiency is generally transient and mild for patients with aldosterone-producing adenoma (APA) after adrenalectomy. We report here a case with prolonged ZG insuffiency requiring long-term mineralocorticoid replacement (MR) therapy.Case report: A 45-years-old female with hypertension and hypokalemia admitted to outpatient clinic with incidentally detected right adrenal adenoma (3 cm) showing sig...

Introduction: Hypogonadism persisting in man with macroprolactinoma requires exogenous testosterone replacement therapy (TRT). But TRT may cause secondary elevations of prolactin. We report here a case of macroprolactinoma and hypogonadotropic hypogonadism with persistently high prolactin level after initiating TRT.Case report: A 28 year-old male was admitted to outpatient clinic with complaints of headache, low libido and blurred vision on left eye for ...

Introduction: Ectopic ACTH syndrome (EAS) is a rare cause of Cushing’s syndrome. EAS is most frequently caused by bronchial carcinoid tumor or small cell lung cancer. Medullary thyroid carcinoma (MTC) is a rare source of EAS, as reported in this case.Case report: A 65-years-old-female with back pain and weight gain referred to our outpatient clinic with determined signs and symptoms of hypercortisolism. She had arterial hypertension, her sister had ...

Introduction: Cushing’s disease (CD) frequently leads to hypogonadotropic hypogonadism by hypercortisolism and hyperandrogenemia. In the literature, there are totally 96 cases of CD and pregnancy. Only four of 11 cases, operated transsphenoidally, were cured. We aimed to present a case of CD developing pregnancy in which hypercortisolism was successfully controlled by transsphenoidal surgery (TSS) in 2nd trimester.Case report: 28 years old female wa...

Introduction: Maturity-onset diabetes of young (MODY) type 2 is caused by mutation of the glucokinase gene. It is characterized by mild fasting hyperglicemia and absence of vascular complications. It is estimated that the incidence of gestational diabetes is 3%. We aimed to present a pregestational diabetic case with MODY-type 2 in pregnancy.Case report: A 38-year-old pregnant woman was referred to our clinic for glycemic regulation at 22th week of gesta...

Introduction: Autoimmune polyendocrine syndromes (APS) are rare endocrinopathies characterized by the coexistence of at least two glandular autoimmune diseases. APS comprise a wide spectrum of autoimmune disorders and are divided into a very rare juvenile (APS type 1) and a more common adult type with (APS 2) or without adrenal failure (APS 3). We present a patient with polyglanduler syndrome type 3a.Case report: A 39-years-old female patient was present...

Introduction: Parathyroid adenoma is the most common cause of primer hyperparathyroidism (PHPT). Mediastinal ectopic parathyroid adenomas constitute about 1–3% of the cases. Brown tumors ocur in less than 2% of the patients with PHPT. Moreover, those skeletal manifestations are even rarely demonstrated with maxillofacial bones involvement.Case presentaton: Here we report a 36-years-old woman presented with approximately 30×26 mm mass growth in ...

Introduction: Congenital adrenal hyperplasia (CAH) is a group of autosomal recessively inherited disorders that are characterised by inactivating mutations at various steps of adrenal steroidogenic pathways causing defective cortisol biosynthesis. 21-Hydroxylase enzyme deficiency (21-OHd) constitutes more than 95% of all CAH cases.Material & Methods: Medical records of patients with all forms of CAH from 19 adult endocrinology clinics located at six ...